{"id":7088,"date":"2023-09-01T18:10:40","date_gmt":"2023-09-01T11:10:40","guid":{"rendered":"https:\/\/loudhdtv.com\/?p=7088"},"modified":"2023-09-01T18:10:40","modified_gmt":"2023-09-01T11:10:40","slug":"the-possible-link-between-ibs-parkinsons-disease","status":"publish","type":"post","link":"https:\/\/loudhdtv.com\/?p=7088","title":{"rendered":"The Possible Link Between IBS &#038; Parkinson&#8217;s Disease"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script><br \/>\n<br \/><img decoding=\"async\" src=\"https:\/\/mindbodygreen-res.cloudinary.com\/image\/upload\/c_crop,x_60,y_0,w_1440,h_810\/c_fill,w_700,h_400,g_auto,q_85,fl_lossy,f_jpg\/org\/l210s58p6jxxfyygr.jpg\" \/><\/p>\n<div>\n<p>Before we dive into these findings, let\u2019s cover the current state of Parkinson&#8217;s research, preceding this study.<\/p>\n<p>The most common suspected cause of Parkinson\u2019s disease is a pathological pattern of Lewy body (LB) protein deposition. These depositions, researchers say, mainly consist of misfolded <em>\u03b1-synuclein<\/em>\u2014a presynaptic neuronal protein that is linked <span data-citation-wrapper=\"\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3281589\/\" data-citation-link=\"\">genetically and neuropathologically to Parkinson&#8217;s disease<\/a><a href=\"#citations\" data-citation-number=\"1\">1<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"11\" height=\"10\" viewbox=\"0 0 11 10\"><path d=\"M10.5616 1.47255C10.7935 1.16327 10.7308 0.724508 10.4216 0.492549C10.1123 0.26059 9.67352 0.323271 9.44156 0.63255L4.41852 7.32996L2.03106 4.54448C1.77947 4.25094 1.33756 4.21694 1.04403 4.46853C0.750497 4.72012 0.716495 5.16203 0.968084 5.45556L3.77335 8.72851C3.81859 8.84955 3.89785 8.9595 4.0089 9.04279C4.09758 9.1093 4.19691 9.15159 4.29895 9.17078C4.51931 9.23643 4.76744 9.19227 4.955 9.03151C5.07764 8.92639 5.15498 8.78804 5.18511 8.64118L10.5616 1.47255Z\"\/><\/svg><\/a><\/span>.\u00a0<\/p>\n<p>Interestingly, the misfolded \u03b1-synuclein has not only been found in the central nervous system but also in the vagus nerve and the enteric nervous system (ENS)\u2014the latter <span data-citation-wrapper=\"\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7495222\/\" data-citation-link=\"\">located within the walls of the GI tract, <\/a><a href=\"#citations\" data-citation-number=\"2\">2<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"11\" height=\"10\" viewbox=\"0 0 11 10\"><path d=\"M10.5616 1.47255C10.7935 1.16327 10.7308 0.724508 10.4216 0.492549C10.1123 0.26059 9.67352 0.323271 9.44156 0.63255L4.41852 7.32996L2.03106 4.54448C1.77947 4.25094 1.33756 4.21694 1.04403 4.46853C0.750497 4.72012 0.716495 5.16203 0.968084 5.45556L3.77335 8.72851C3.81859 8.84955 3.89785 8.9595 4.0089 9.04279C4.09758 9.1093 4.19691 9.15159 4.29895 9.17078C4.51931 9.23643 4.76744 9.19227 4.955 9.03151C5.07764 8.92639 5.15498 8.78804 5.18511 8.64118L10.5616 1.47255Z\"\/><\/svg><\/a><\/span>extending from the esophagus to the anal canal, in people with Parkinson\u2019s disease.<\/p>\n<p>The new study, published in <em>BMJ Journals<\/em>\u00a0set out to explore the possibility of Parkinson\u2019s disease <em>originating<\/em> in the gut, based on the fact that misfolded proteins have been found in the GI tract and esophagus.<\/p>\n<p>In order to study this, researchers looked for Parkinson&#8217;s patients who had digestive symptoms before being diagnosed with the brain disorder.<\/p>\n<p>The researchers analyzed a combination of case-control studies of 24,624 Parkinson&#8217;s patients and a cohort study utilizing a US-based nationwide medical record network. They looked for a broad range of both GI symptoms and GI diagnoses that appeared before Parkinson\u2019s diagnoses.<\/p>\n<\/div>\n<div data-type=\"_mgwidget\" data-widget-id=\"1675549\">\r\n<\/div>\r\n<script>(function(w,q){w[q]=w[q]||[];w[q].push([\"_mgc.load\"])})(window,\"_mgq\");\r\n<\/script>\r\n\n","protected":false},"excerpt":{"rendered":"<p>Before we dive into these findings, let\u2019s cover the current state of Parkinson&#8217;s research, preceding this study. The most common suspected cause of Parkinson\u2019s disease is a pathological pattern of Lewy body (LB) protein deposition. These depositions, researchers say, mainly consist of misfolded \u03b1-synuclein\u2014a presynaptic neuronal protein that is linked genetically and neuropathologically to Parkinson&#8217;s &hellip;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[80,74,147,79],"class_list":["post-7088","post","type-post","status-publish","format-standard","hentry","category-lifestyle","tag-brain","tag-digestion","tag-mbg-brain-health","tag-news"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/posts\/7088","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=7088"}],"version-history":[{"count":0,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/posts\/7088\/revisions"}],"wp:attachment":[{"href":"https:\/\/loudhdtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=7088"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=7088"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=7088"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}