{"id":4936,"date":"2023-06-21T15:20:55","date_gmt":"2023-06-21T08:20:55","guid":{"rendered":"https:\/\/loudhdtv.com\/?p=4936"},"modified":"2023-06-21T15:20:55","modified_gmt":"2023-06-21T08:20:55","slug":"study-finds-melatonin-may-worsen-inflammatory-bowel-disease-symptoms","status":"publish","type":"post","link":"https:\/\/loudhdtv.com\/?p=4936","title":{"rendered":"Study Finds Melatonin May Worsen Inflammatory Bowel Disease Symptoms"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script><br \/>\n<br \/><img decoding=\"async\" src=\"https:\/\/mindbodygreen-res.cloudinary.com\/image\/upload\/c_crop,x_0,y_161,w_2000,h_1124\/c_fill,w_700,h_400,g_auto,q_85,fl_lossy,f_jpg\/org\/v8fcta11clfi9ov29.jpg\" \/><\/p>\n<div>\n<p>For this study, researchers wanted to investigate the connections between IBD, supplementing melatonin, and the subsequent\u00a0immune responses and bacterial compositions in the guts of mice. To do so, they created a mouse model of IBD, administering melatonin to a portion of them.<\/p>\n<p>Based on their analysis, melatonin actually made symptoms <em>and<\/em> recovery worse for the mice who had been administered melatonin, showing worsened gut inflammation, and during remission, slower recovery.<\/p>\n<p>Namely, the mice who&#8217;d been administered melatonin showed notable signs of colitis aggravation, delayed recovery, and increased inflammatory markers, which the study authors say confirm the harmful effects of melatonin supplementation on a disrupted gut barrier.<\/p>\n<p>While these findings have yet to be replicated in humans, study co-author and immunologist Cristina Ribeiro de Barros Cardoso Ph.D. notes that people should be scrutinous when it comes to hormonal supplements.<\/p>\n<p>\u201cOur study shows that people should be careful about taking hormone supplements and that the ingestion of melatonin as a supplement can have adverse effects on health,\u201d\u00a0she says in <a href=\"https:\/\/www.medicalnewstoday.com\/articles\/melatonin-used-to-promote-sleep-may-worsen-inflammatory-bowel-disease-symptoms\" target=\"_blank\" class=\"mbg-track-event\" data-track-event-types=\"click\" data-track-type=\"article-link\" data-track-prop-element-id=\"in-body-link\" data-track-prop-label=\"page_type | element_id\" data-track-prop-category=\"Link\" data-track-prop-link=\"https:\/\/www.medicalnewstoday.com\/articles\/melatonin-used-to-promote-sleep-may-worsen-inflammatory-bowel-disease-symptoms\" rel=\"noopener\">a news release<\/a>, adding, \u201c[Melatonin is] a hormone and regulation of the interaction between all hormones and the immune system is very delicate.\u201d<\/p>\n<\/div>\n<div data-type=\"_mgwidget\" data-widget-id=\"1675549\">\r\n<\/div>\r\n<script>(function(w,q){w[q]=w[q]||[];w[q].push([\"_mgc.load\"])})(window,\"_mgq\");\r\n<\/script>\r\n\n","protected":false},"excerpt":{"rendered":"<p>For this study, researchers wanted to investigate the connections between IBD, supplementing melatonin, and the subsequent\u00a0immune responses and bacterial compositions in the guts of mice. To do so, they created a mouse model of IBD, administering melatonin to a portion of them. Based on their analysis, melatonin actually made symptoms and recovery worse for the &hellip;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[67,130,79,48],"class_list":["post-4936","post","type-post","status-publish","format-standard","hentry","category-lifestyle","tag-gut-health","tag-inflammation","tag-news","tag-sleep"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/posts\/4936","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4936"}],"version-history":[{"count":0,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/posts\/4936\/revisions"}],"wp:attachment":[{"href":"https:\/\/loudhdtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4936"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4936"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4936"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}