{"id":15035,"date":"2025-09-02T05:04:30","date_gmt":"2025-09-01T22:04:30","guid":{"rendered":"https:\/\/loudhdtv.com\/?p=15035"},"modified":"2025-09-02T05:04:30","modified_gmt":"2025-09-01T22:04:30","slug":"a-fascinating-paradox-concerning-nutrition-disease-risk-and-survival-bionicoldguy","status":"publish","type":"post","link":"https:\/\/loudhdtv.com\/?p=15035","title":{"rendered":"A Fascinating Paradox Concerning Nutrition, Disease Risk, And Survival \u2013 BionicOldGuy"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script><br \/>\n<\/p>\n<div id=\"post-12827\">\n\t\t\t<!-- .entry-header -->\t\t<!-- .entry-meta --><\/p>\n<div class=\"entry-content\">\n<p>Dr. Raphael Cuomo, a professor at the University of California, San Diego School of Medicine who\u2019s work I\u2019ve mentioned <a href=\"https:\/\/bionicoldguy.home.blog\/2025\/07\/15\/crave-the-hidden-biology-of-addiction-and-cancer\/\">previously<\/a>, called my attention to a fascinating recent paper he wrote. It is about \u201cnutritional epidemiology risk\u2013survival paradox\u201d, for which the term \u201cCuomo\u2019s Paradox\u201d has also been coined. There is also a good summary of the paradox in <a href=\"https:\/\/www.youtube.com\/watch?v=qW_Q09R0ON0\">this youtube video<\/a>. To summarize, there are health and nutrition recommendations to reduce the risk of acquiring conditions like cardiovascular disease and certain types of cancer. But the paradox is that if you already have one of these diseases, these same recommendations can become contraindicated because they can now increase the risk of dying from the disease. An important exemple is obesity, which is well known as a risk factor. But carrying some extra pounds can be protective after you already have a disease.<\/p>\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" data-attachment-id=\"12835\" data-permalink=\"https:\/\/bionicoldguy.home.blog\/2025\/08\/30\/a-fascinating-paradox-concerning-nutrition-disease-risk-and-survival\/image-454\/\" data-orig-file=\"https:\/\/bionicoldguy.home.blog\/wp-content\/uploads\/2025\/09\/image-2.png\" data-orig-size=\"1004,588\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"image\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/bionicoldguy.home.blog\/wp-content\/uploads\/2025\/09\/image-2.png?w=300\" data-large-file=\"https:\/\/bionicoldguy.home.blog\/wp-content\/uploads\/2025\/09\/image-2.png?w=1004\" width=\"1004\" height=\"588\" src=\"https:\/\/bionicoldguy.home.blog\/wp-content\/uploads\/2025\/09\/image-2.png?w=1004\" alt=\"\" class=\"wp-image-12835\"\/><figcaption class=\"wp-element-caption\"><strong><em>Example of Cuomo\u2019s Paradox: Effect of being overweight, consuming alcohol, and cholesterol on patient\u2019s with heart failure<\/em><\/strong> (<a href=\"https:\/\/www.youtube.com\/watch?v=qW_Q09R0ON0\">https:\/\/www.youtube.com\/watch?v=qW_Q09R0ON0<\/a>)<\/figcaption><\/figure>\n<p>Evidence for more effects like this (like the effects of alcohol and cholesterol) are covered in the paper. Dr. Cuomo is careful to point out that we may not yet have enough information to change health recommendations, but more research is definitely needed on this intriguing paradox. <a href=\"https:\/\/jn.nutrition.org\/article\/S0022-3166(25)00472-9\/fulltext\">Here is a link to the full text in the Journal of Nutrition.<\/a><\/p>\n<div id=\"jp-post-flair\" class=\"sharedaddy sd-like-enabled sd-sharing-enabled\">\n<div class=\"sharedaddy sd-sharing-enabled\">\n<div class=\"robots-nocontent sd-block sd-social sd-social-official sd-sharing\">\n<h3 class=\"sd-title\">Share this:<\/h3>\n<div class=\"sd-content\">\n<ul>\n<li class=\"share-linkedin\"\/>\n<li class=\"share-facebook\"\/>\n<li class=\"share-pinterest\">\n<div class=\"pinterest_button\"><a href=\"https:\/\/www.pinterest.com\/pin\/create\/button\/?url=https%3A%2F%2Fbionicoldguy.home.blog%2F2025%2F08%2F30%2Fa-fascinating-paradox-concerning-nutrition-disease-risk-and-survival%2F&amp;media=https%3A%2F%2Fbionicoldguy.home.blog%2Fwp-content%2Fuploads%2F2025%2F09%2Fimage-2.png&amp;description=A%20Fascinating%20Paradox%20Concerning%20Nutrition%2C%20Disease%20Risk%2C%20And%20Survival\" data-pin-do=\"buttonPin\" data-pin-config=\"beside\"><img decoding=\"async\" src=\"https:\/\/assets.pinterest.com\/images\/pidgets\/pinit_fg_en_rect_gray_20.png\"\/><\/a><\/div>\n<\/li>\n<li class=\"share-end\"\/><\/ul>\n<\/div>\n<\/div>\n<\/div>\n<p><h3 class=\"jp-relatedposts-headline\"><em>Related<\/em><\/h3>\n<\/p>\n<\/div><\/div>\n<p><!-- .entry-content --><\/p>\n<p>\t<!-- .entry-footer --><\/p>\n<div class=\"entry-author-wrapper\">\n<div class=\"entry-author author-avatar-show\">\n<div class=\"author-avatar\">\n\t\t\t\t<img referrerpolicy=\"no-referrer\" alt=\"Unknown's avatar\" src=\"https:\/\/2.gravatar.com\/avatar\/25e2835f41aad499102b7dccdf750ee9842e9a75fa2931cd1ba6fa84c47eafd5?s=80&amp;d=&amp;r=G\" srcset=\"https:\/\/2.gravatar.com\/avatar\/25e2835f41aad499102b7dccdf750ee9842e9a75fa2931cd1ba6fa84c47eafd5?s=80&amp;d=&amp;r=G 1x, https:\/\/2.gravatar.com\/avatar\/25e2835f41aad499102b7dccdf750ee9842e9a75fa2931cd1ba6fa84c47eafd5?s=120&amp;d=&amp;r=G 1.5x, https:\/\/2.gravatar.com\/avatar\/25e2835f41aad499102b7dccdf750ee9842e9a75fa2931cd1ba6fa84c47eafd5?s=160&amp;d=&amp;r=G 2x, https:\/\/2.gravatar.com\/avatar\/25e2835f41aad499102b7dccdf750ee9842e9a75fa2931cd1ba6fa84c47eafd5?s=240&amp;d=&amp;r=G 3x, https:\/\/2.gravatar.com\/avatar\/25e2835f41aad499102b7dccdf750ee9842e9a75fa2931cd1ba6fa84c47eafd5?s=320&amp;d=&amp;r=G 4x\" class=\"avatar avatar-80\" height=\"80\" width=\"80\" loading=\"lazy\" decoding=\"async\"\/>\t\t\t<\/div>\n<p><!-- .author-avatar --><\/p>\n<p><h2 class=\"author-title\">\n\t\t\t\t\tPublished by <span class=\"author-name\">BionicOldGuy<\/span>\t\t\t\t<\/h2>\n<\/p>\n<p><!-- .author-heading --><\/p>\n<p class=\"author-bio\">\n\t\t\t\tI am a Mechanical Engineer born in 1953, Ph. D, Stanford, 1980. I have been active in the mechanical CAE field for decades. I also have a lifelong interest in outdoor activities and fitness. I have had both hips replaced and a heart valve replacement due to a genetic condition. This blog chronicles my adventures in staying active despite these bumps in the road.\t\t\t\t<a class=\"author-link\" href=\"https:\/\/bionicoldguy.home.blog\/author\/richardking2213\/\" rel=\"author\"><br \/>\n\t\t\t\t\tView all posts by BionicOldGuy\t\t\t\t<\/a>\n\t\t\t<\/p>\n<p><!-- .author-bio -->\n\t\t<\/div>\n<p><!-- .entry-auhtor --><\/p>\n<p>\n\t\t\t<strong>Published<\/strong><br \/>\n\t\t\t<time class=\"entry-date published\" datetime=\"2025-08-30T07:09:00-07:00\">August 30, 2025<\/time><time class=\"updated\" datetime=\"2025-09-01T14:30:09-07:00\">September 1, 2025<\/time>\t\t<\/p>\n<p><!-- .site-posted-on -->\n\t<\/div>\n<\/div>\n<p><script>(function(d, s, id) { var js, fjs = d.getElementsByTagName(s)[0]; if (d.getElementById(id)) return; js = d.createElement(s); js.id = id; js.src=\"https:\/\/connect.facebook.net\/en_US\/sdk.js#xfbml=1&amp;appId=249643311490&version=v2.3\"; fjs.parentNode.insertBefore(js, fjs); }(document, 'script', 'facebook-jssdk'));<\/script><br \/>\n<br \/><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script><br \/>\n<br \/><a href=\"https:\/\/bionicoldguy.home.blog\/2025\/08\/30\/a-fascinating-paradox-concerning-nutrition-disease-risk-and-survival\/\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Raphael Cuomo, a professor at the University of California, San Diego School of Medicine who\u2019s work I\u2019ve mentioned previously, called my attention to a fascinating recent paper he wrote. It is about \u201cnutritional epidemiology risk\u2013survival paradox\u201d, for which the term \u201cCuomo\u2019s Paradox\u201d has also been coined. There is also a good summary of the &hellip;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-15035","post","type-post","status-publish","format-standard","hentry","category-fitness"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/posts\/15035","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=15035"}],"version-history":[{"count":0,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/posts\/15035\/revisions"}],"wp:attachment":[{"href":"https:\/\/loudhdtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=15035"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=15035"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=15035"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}