{"id":13503,"date":"2025-03-04T21:50:57","date_gmt":"2025-03-04T14:50:57","guid":{"rendered":"https:\/\/loudhdtv.com\/?p=13503"},"modified":"2025-03-04T21:50:57","modified_gmt":"2025-03-04T14:50:57","slug":"macrocytosis-what-causes-it-mayo-clinic","status":"publish","type":"post","link":"https:\/\/loudhdtv.com\/?p=13503","title":{"rendered":"Macrocytosis: What causes it? &#8211; Mayo Clinic"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script><br \/>\n<\/p>\n<div id=\"main-content\" tabindex=\"-1\" role=\"main\">\n<!--googleon: all--><\/p>\n<p><h2>What causes enlarged red blood cells?<\/h2>\n<p>\tAnswer From Rajiv K. Pruthi, M.B.B.S.<\/p>\n<p>Macrocytosis is a term used to describe red blood cells that are larger than normal. Also known as megalocytosis or macrocythemia, this condition typically causes no signs or symptoms and is usually detected incidentally on routine blood tests.<\/p>\n<p>Macrocytosis isn&#8217;t a specific disease, but it may indicate an underlying problem that requires medical evaluation. Common causes of macrocytosis include:<\/p>\n<ul>\n<li>Vitamin B-12 deficiency<\/li>\n<li>Folate deficiency<\/li>\n<li>Liver disease<\/li>\n<li>Alcoholism<\/li>\n<li>Hypothyroidism<\/li>\n<li>A side effect of certain medications, such as those used to treat cancer, seizures and autoimmune disorders<\/li>\n<li>Increased red blood cell production by the bone marrow to correct anemia, for example, after blood loss<\/li>\n<li>An underlying bone marrow cancer called myelodysplastic syndrome<\/li>\n<\/ul>\n<p>If you have macrocytosis, blood tests can help determine its cause. In some cases, it may be necessary to remove a sample of your bone marrow \u2014 the spongy tissue inside your bones \u2014 for testing.<\/p>\n<p>Management of macrocytosis consists of finding and treating the underlying cause. In the case of vitamin B-12 or folate deficiency, treatment may include diet modification and dietary supplements or injections. If the underlying cause is resulting in severe anemia, you might need a blood transfusion.<\/p>\n<div class=\"bioHighlight\">\n<div>\n<p>With <\/p>\n<p class=\"name\">\n\tRajiv K. Pruthi, M.B.B.S.<\/p>\n<\/p><\/div>\n<\/p><\/div>\n<p><!--googleoff: all--><\/p>\n<div class=\"contentbox no-border\">\n<link rel=\"stylesheet\" href=\"http:\/\/www.mayoclinic.org\/~\/media\/kcms\/ux\/css\/newslettereh.css\"\/>\n<article>\n<div class=\"row\">\n<div class=\"content\">\n<p>\n                \u00a0\n            <\/p>\n<div class=\"myc-subscription-form\" data-sending-url=\"https:\/\/s74881809.t.eloqua.com\/e\/f2\" data-name-form=\"MKT.PES.HC.EmailSignup2\" data-last-step=\"true\">\n<div class=\"myc-step-container\">\n<div class=\"myc-subscription-step-wrapper\" id=\"first-step\" aria-describedby=\"formTitle\" tabindex=\"-1\">\n<div class=\"myc-form-comp-wrapper\" tabindex=\"-1\" id=\"gralError\" aria-describedby=\"errorBanner\" hidden=\"\">\n<p role=\"alert\" id=\"errorBanner\" class=\"myc-error-header\">There is a problem with<br \/>\n                                information submitted for this request. 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Macrocytosis\/macrocytic anemia. https:\/\/www.uptodate.com\/contents\/search. Accessed Nov. 25, 2024.<\/li>\n<li>Shafaat SS, et al. A cross-sectional study for the spectrum of clinic diagnosis in patents presenting with macrocytosis. Cureus. 2024; doi:10.7759\/cureus.54702.<\/li>\n<li>Goldman L, et al., eds. Megaloblastic anemias. In Goldman-Cecil Medicine. 27th ed. Elsevier, 2024. https:\/\/www.clinicalkey.com. Accessed Nov. 25, 2024.<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<p><a href=\"\" class=\"blocklink\">See more Expert Answers<\/a><\/p>\n<p><!--googleoff: all--><\/p>\n<p><!--googleon: all--><\/p>\n<p><!--googleoff: all--><\/p>\n<p><!--googleon: all--><\/p>\n<\/div>\n<p>&#13;<br \/>\n                    .&#13;\n                <\/p>\n<p><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script><br \/>\n<br \/><a href=\"http:\/\/www.mayoclinic.org\/macrocytosis\/expert-answers\/faq-20058234\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>What causes enlarged red blood cells? Answer From Rajiv K. Pruthi, M.B.B.S. Macrocytosis is a term used to describe red blood cells that are larger than normal. Also known as megalocytosis or macrocythemia, this condition typically causes no signs or symptoms and is usually detected incidentally on routine blood tests. Macrocytosis isn&#8217;t a specific disease, &hellip;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-13503","post","type-post","status-publish","format-standard","hentry","category-health"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/posts\/13503","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=13503"}],"version-history":[{"count":0,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=\/wp\/v2\/posts\/13503\/revisions"}],"wp:attachment":[{"href":"https:\/\/loudhdtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=13503"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=13503"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/loudhdtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=13503"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}